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Would using a USB Hub for UART communication cause any issues?

I want to get a USB hub because my laptop doesn’t have enough USB ports. I’ll connect a keyboard, mouse, a USB cable for UART communication, and another cable for programming the FPGA. So let’s say I connect 4 USB cables. What concerns me is that ultimately these 4 USB inputs are connected to the same USB port at the final. In this case, would it be possible to both program the FPGA and communicate via UART through the same USB port? and at the same i will be using keyobard, mouse I hope I’ve explained it clearly.