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UART reading performance at high baud rates (FTDI + Windows)

I have an FPGA digitizer connected via FTDI FT4232 USB-UART converter to my Windows 10 computer. The communication speed is 5 Mega Bauds, 8N1. I am trying to read 1048576 bytes of data which is sent as a response to a simple text command. Data is protected by a CRC32 checksum (transferred using another command).